A multi-phenotypic cancer model with cell plasticity
نویسندگان
چکیده
منابع مشابه
A multi-phenotypic cancer model with cell plasticity.
The conventional cancer stem cell (CSC) theory indicates a hierarchy of CSCs and non-stem cancer cells (NSCCs), that is, CSCs can differentiate into NSCCs but not vice versa. However, an alternative paradigm of CSC theory with reversible cell plasticity among cancer cells has received much attention very recently. Here we present a generalized multi-phenotypic cancer model by integrating cell p...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2014
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2014.04.039